Ampio Pharmaceuticals, Inc. Announces Closing of Registered Direct Offering

ENGLEWOOD, CO., June 7, 2017 /PRNewswire/ — Ampio Pharmaceuticals, Inc. (NYSE MKT: AMPE) (“Ampio”) today announced that it has closed its previously announced registered direct offering of 10,990,245 shares of common stock and warrants to purchase up to 10,990,245 shares of common stock. The shares and warrants were sold in units, each of which is comprised of one share and a warrant to purchase one share of common stock. The purchase price per unit in the offering was $0.60. The warrants are exercisable six months following the date of issuance and will expire on the fifth anniversary of the initial date that the warrants become exercisable. The warrants will have an exercise price of $0.76.

Gross proceeds of the offering are approximately $6.6 million. Ampio intends to use the proceeds from the offering for working capital and general corporate purposes, including funding of the Ampion™ clinical trial.

Joseph Gunnar & Co., LLC and Fordham Financial Management, Inc. acted as placement agents for the offering.

The sale of the common stock and warrants were offered by the Company pursuant to a shelf registration statement on Form S-3 (Registration No. 333-217094), which was declared effective by the Securities and Exchange Commission (the “SEC”) on April 20, 2017. A final prospectus supplement was filed with the SEC and forms part of the effective registration statement.  Copies of the final prospectus supplement and accompanying prospectus relating to this offering may be obtained by contacting Joseph Gunnar & Co., LLC, Prospectus Department, 30 Broad Street, 11th Floor, New York, NY 10004, telephone 212-440-9600, email: prospectus@jgunnar.com or Fordham Financial Management, Inc. at: 17 Battery Place, Suite 643, New York, NY 10004, by telephone at: 212 732-8500, or by email at: Compliance@FordhamFinancial.com.

This press release does not and shall not constitute an offer to sell or the solicitation of an offer to buy any securities, nor shall there be any sale of these securities in any state or jurisdiction in which such an offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities law of any such state or jurisdiction.

About Ampio Pharmaceuticals:
Ampio Pharmaceuticals, Inc. is a clinical trial stage biopharmaceutical company primarily focused on the development of therapies to treat prevalent inflammatory conditions for which there are limited treatment options.  We are developing compounds that decrease inflammation by (i) inhibiting specific pro-inflammatory compounds by affecting specific pathways at the protein expression and at the transcription level; (ii) activating specific phosphatase or depletion of the available phosphate needed for the inflammation process; and (iii) decreasing vascular permeability.

Investor Contact:
Gregory A. Gould
Chief Financial Officer
Ampio Pharmaceuticals, Inc.
Direct: (720) 437-6513
Email: ggould@ampiopharma.com

Forward Looking Statements:
This press release contains “forward-looking statements,” within the meaning of the Private Securities Litigation Reform Act of 1995, regarding, among other things, the proposed registered direct offering of Ampio’s common stock and warrants. Such forward-looking statements are based on current expectations and involve inherent risks and uncertainties, including factors that could delay, divert or change any of them, and could cause actual results to differ materially from those projected in its forward-looking statements. Meaningful factors which could cause actual results to differ are discussed in the risks and uncertainties detailed from time to time in Ampio’s filings with the Securities and Exchange Commission, including without limitation, under Ampio’s Annual Report on Form 10-K and Quarterly Reports on Form 10-Q.  Ampio undertakes no obligation to revise or update these forward-looking statements, whether as a result of new information, future events or otherwise.